Ibogaine reduces severe bipolar depression within 15 days in one case study

A case study found that microdosing ibogaine reduced the effects of severe bipolar depression within 15 days.

Published in the Brazilian Journal of Psychiatry, the work, which had the participation of Dr. Bruno Rasmussen Chaves, Medical Director of Beneva, described the effects of the substance on a 47-year-old woman with a 20-year history of bipolar disorder. During treatment, performed in a private clinic, two highly pure ibogaine capsules, containing 4 mg each (approximately 1% of a complete conventional single dose), were administered twice daily for 60 days.

“After 15 days, we observed overall improvement compared to the initial assessment, as well as some functional recovery. She reported increased mental clarity, organized thinking, and positive prospects regard-ing the future”, the researchers wrote. “After 43 days, she reported a boosted appetite and initiative to engage in professional activities. Even 30 days after discontinuation of ibogaine (day 60), she had sustained improvement, which persisted throughday 90.”

While robust research on ibogaine microdosing for psychiatric disorders is still lacking, the report suggests that the practice could be a potentially innovative treatment alternative.

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